The Art of Cheating in the 21st Millennium: Innovative Mechanisms and Insidious Ploys in Academic Deceit

Cheating is rampant throughout academia, with no hard evidence suggesting that such pedagogic deceit will wane. Cheating is most insidious on the college level, where such academic deceit has evolved from perhaps its basic pattern of merely peeking at another student’s examination, to planned deceit employing sophisticated subterfuges and interplay between two or more co-conspirators. Importantly, cheating per se may not necessarily be student initiated, but fostered by college/university staff for purposes of institutional or personal financial gain. Statistical studies (e.g., demographics) in complement with sociological and psychological factors associated with cheating have been previously described. This review does not attempt to embellish the plethora of earlier reviews or research on the subject, but stands unique in that specific case reports and recent findings are presented describing techniques or mechanisms used in the performance of academic deceit to by-pass university codes of ethics. The purpose of this work is to acquaint adjunct staff, tenure track, and perhaps senior faculty in the biological sciences and other disciplines to those mechanistic approaches used by students and college staff as well, in the commission of academic fraud. Suggestions are proposed to help detect and reduce academic deceit

Comparison of α-glucosyl hesperidin of citrus fruits and epigallocatechin gallate of green tea on the Loss of Rotavirus Infectivity in Cell Culture

A number of secondary plant metabolites (e.g., flavonoids) possess antiviral/antimicrobial activity. Most flavonoids, however, are difficult to study, as they are immiscible in water-based systems. The relatively new semisynthetic α-glucosyl hesperitin (GH), and the natural plant product epigallocatechin gallate (EGCG) are unique among most flavonoids, as these flavonoids are highly soluble. The antiviral activity of these plant metabolites were investigated using the rotavirus as a model enteric virus system. Direct loss of virus structural integrity in cell-free suspension and titration of amplified RTV in host cell cultures was measured by a quantitative enzyme-linked immunosorbent assay (qEIA). After 30 min. 100 × 103 μg/ml GH reduced RTV antigen levels by ca. 90%. The same compound reduced infectivity (replication in cell culture) by a similar order of magnitude 3 to 4 days post inoculation. After 3 days in culture, EGCG concentrations of 80, 160, and 320 μg/ml reduced RTV infectivity titer levels to ca. 50, 20, and 15% of the control, respectively. Loss of RTV infectivity titers occurred following viral treatment by parallel testing of both GH and EGCG, with the latter, markedly more effective. Cytotoxicity testing showed no adverse effects by the phenolic concentrations used in this study. The unique chemical structure of each flavonoid rather than each phenolic’s inherent solubility may be ascribed to those marked differences between each molecule’s antiviral (anti-RTV) effects. The solubility of EGCG and GH obviated our need to use potentially confounding or obfuscating carrier molecules (e.g., methanol, ethanol, DMSO) denoting our use of a pure system environ. Our work further denotes the need to address the unique chemical nature of secondary plant metabolites before any broad generalizations in flavonoid (antiviral) activity may be proposed